Introducing: GutFeeling

The Utrecht 2025 iGEM team is excited to announce this year’s project! After being absent from the #iGEM scene for seven years we wanted to come back strong with a novel drug delivery tool.

#GutFeeling will be a self-sustained, drug delivery system that resides in the gut. We aim to engineer a commensal bacterium to autonomously produce and secrete therapeutic molecules within the gastrointestinal tract at a consistent dosage.

Our goal is not only to engineer this bacterium, but we will also be #FishingForSolutions by testing the application of our tool in vivo. As a proof of concept, we will use our bacterium to express a controlled dosage of L-dopa in the zebrafish gut.

We can’t wait to take you along on this exciting journey!

More info coming soon…